495
Abstract Views
212
PDF Download
Case-Study

Therapy of resistant hypertension in patients with chronic kidney disease complications of anemia in hemodialysis: a case report

Yenry Sumarlim University of Surabaya, Indonesia Correspondence masteryen888@gmail.com
,
Emilia Gan University of Surabaya, Indonesia Correspondence gan.emilia@gmail.com
,
Desantika Wuryana Mardi Waluyo Regional Public Hospital, Indonesia Correspondence wuryana.desantika@gmail.com
,
M. Hari Pristantiningtyas Mardi Waluyo Regional Public Hospital, Indonesia Correspondence maditoo@gmail.com
,
Herya Putra Dharma Mardi Waluyo Regional Public Hospital, Indonesia Correspondence heryaputra@gmail.com
,
Muhammad Muchlis Regional Public Hospital, Indonesia Correspondence paklurah010670@gmail.com
,
Jainuri Erik Pratama Dr. Kariadi Central General Hospital, Indonesia Correspondence erik.rssa@gmail.com
,
Adji Prayitno Setiadi University of Surabaya, Indonesia Correspondence adji_ps@staff.ubaya.ac.id
,
Marisca Evalina Gondokesumo Universitas Surabaya, Indonesia Correspondence marisca@staff.ubaya.ac.id
Pages 61-65
Browse this journal

Abstract

Chronic Kidney Disease (CKD) is closely related to hypertension. Increasing the severity of CKD is associated with more difficult blood pressure control. Appropriate therapeutic management is needed to prevent complications due to uncontrolled hypertension. We report the case of a 78-year-old female patient with a diagnosis of hypertension and end-stage CKD with a history of undergoing hemodialysis for 4 years. The patient has been taking antihypertensive drugs such as Angiotensin Receptor Blockers, Calcium Channel Blockers and Diuretics. However, the administration of three antihypertensive drugs still could not help achieve the expected blood pressure target where the systolic blood pressure was still above 160 mmHg. The patient also has anemia as a common complication of chronic kidney disease. Appropriate management of therapy with fourth-line therapy and hemoglobin repair is necessary to achieve improved clinical outcomes and reduce renal worsening.

There is no Figure or data content available for this article

References

  • Agarwal, R., Flynn, J., Pogue, V., Rahman, M., Reisin, E., & Weir, M. R. (2014). Assessment and management of hypertension in patients on dialysis. Journal of the American Society of Nephrology : JASN, 25(8), 1630–1646. https://doi.org/10.1681/ASN.2013060601
  • Ameer O. Z. (2022). Hypertension in chronic kidney disease: What lies behind the scene. Frontiers in pharmacology, 13, 949260. https://doi.org/10.3389/fphar.2022.949260
  • Ammirati A. L. (2020). Chronic Kidney Disease. Revista da Associacao Medica Brasileira (1992), 66Suppl 1(Suppl 1), s03–s09. https://doi.org/10.1590/1806-9282.66.S1.3
  • Anna Forbes, Hugh Gallagher. Clinical Medicine Mar 2020, 20 (2) 128-132; DOI: 10.7861/clinmed.cg.20.2
  • Basile, D. P., Anderson, M. D., & Sutton, T. A. (2012). Pathophysiology of acute kidney injury. Comprehensive Physiology, 2(2), 1303–1353. https://doi.org/10.1002/cphy.c110041
  • Carey R. M., Calhoun, D. A., Bakris, G. L., Brook, R. D., Daugherty, S. L., Dennison-Himmelfarb, C. R., Egan, B. M., Flack, J. M., Gidding, S. S., Judd, E., Lackland, D. T., Laffer, C. L., Newton-Cheh, C., Smith, S. M., Taler, S. J., Textor, S. C., Turan, T. N., & White, W. B. (2018). Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association. Hypertension, 72(5). https://doi.org/10.1161/HYP.0000000000000084
  • Chen, T. K., Knicely, D. H., & Grams, M. E. (2019). Chronic Kidney Disease Diagnosis and Management: A Review. JAMA, 322(13), 1294–1304. https://doi.org/10.1001/jama.2019.14745
  • Delacroix, S., & Chokka, R. G. (2014). Hypertension: Pathophysiology and Treatment. Journal of Neurology & Neurophysiology, 05(06). https://doi.org/10.4172/2155-9562.1000250
  • Delong C, Sharma S. Physiology, Peripheral Vascular Resistance. [Updated 2023 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK538308/
  • Doumas, M., Imprialos, K. P., Kallistratos, M. S., & Manolis, A. J. (2020). Recent advances in understanding and managing resistant/refractory hypertension. F1000Research, 9, 169. https://doi.org/10.12688/f1000research.21669.1
  • Fay, K. S., & Cohen, D. L. (2021). Resistant Hypertension in People With CKD: A Review. American Journal of Kidney Diseases, 77(1), 110-121. https://doi.org/10.1053/j.ajkd.2020.04.017
  • Hamrahian, S. M., & Falkner, B. (2016). Hypertension in Chronic Kidney Disease (pp. 307-325). https://doi.org/10.1007/5584_2016_84
  • Irawan, A. (2014). Increase of Serum Creatinine as the Outcome of ACEi or ARB Use. Indonesian Journal of Clinical Pharmacy, 3(3), 82-87. https://doi.org/10.15416/ijcp.2014.3.3.82
  • James, P. A., Oparil, S., Carter, B. L., Cushman, W. C., Dennison-Himmelfarb, C., Handler, J., Lackland, D. T., LeFevre, M. L., MacKenzie, T. D., Ogedegbe, O., Smith, S. C., Svetkey, L. P., Taler, S. J., Townsend, R. R., Wright, J. T., Narva, A. S., & Ortiz, E. (2014). 2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults. JAMA, 311(5), 507. https://doi.org/10.1001/jama.2013.284427
  • KDIGO, 2013. https://kdigo.org/guidelines/ckd-evaluation-and-management
  • Khan, Y. H., Sarriff, A., Adnan, A. S., Khan, A. H., & Mallhi, T. H. (2016). Chronic Kidney Disease, Fluid Overload and Diuretics: A Complicated Triangle. PloS one, 11(7), e0159335. https://doi.org/10.1371/journal.pone.0159335
  • Kim, C. S., Choi, H. S., Bae, E. H., Kim, S. W., & Ma, S. K. (2019). Optimal blood pressure target and measurement in patients with chronic kidney disease. The Korean Journal of Internal Medicine, 34(6), 1181-1187. https://doi.org/10.3904/kjim.2019.164
  • Ku, E., Lee, B. J., Wei, J., & Weir, M. R. (2019). Hypertension in CKD: Core Curriculum 2019. American Journal of Kidney Diseases, 74(1), 120-131. https://doi.org/10.1053/j.ajkd.2018.12.044
  • Murdeshwar HN, Anjum F. Hemodialysis. [Updated 2023 Apr 27]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK563296/
  • Oh, S. W., & Han, S. Y. (2015). Loop Diuretics in Clinical Practice. Electrolyte & blood pressure : E & BP, 13(1), 17–21. https://doi.org/10.5049/EBP.2015.13.1.17
  • Pugh, D., Gallacher, P. J., & Dhaun, N. (2019). Management of Hypertension in Chronic Kidney Disease. Drugs, 79(4), 365–379. https://doi.org/10.1007/s40265-019-1064-1
  • Rabbani, R., Noel, E., Boyle, S., Balina, H., Ali, S., Fayoda, B., & Khan, W. A. (2022). Role of Antihypertensives in End-Stage Renal Disease: A Systematic Review. Cureus, 14(7), e27058. https://doi.org/10.7759/cureus.27058
  • Stern, A., Sachdeva, S., Kapoor, R., Singh, J., & Sachdeva, S. (2014). High Blood Pressure in Dialysis Patients: Cause, Pathophysiology, Influence on Morbidity, Mortality and Management. JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH. https://doi.org/10.7860/JCDR/2014/8253.4471
  • Tobe, S. W., & Lewanczuk, R. (2009). Resistant hypertension. The Canadian journal of cardiology, 25(5), 315–317. https://doi.org/10.1016/s0828-282x(09)70496-9
  • Trammel JE, Sapra A. Physiology, Systemic Vascular Resistance. [Updated 2023 Jul 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK556075/
  • van Buren, P. N. (2016). Evaluation and Treatment of Hypertension in End-Stage Renal Disease Patients on Hemodialysis. Current Cardiology Reports, 18(12), 125. https://doi.org/10.1007/s11886-016-0805-y
  • Williams, B., MacDonald, T. M., Morant, S., Webb, D. J., Sever, P., McInnes, G., Ford, I., Cruickshank, J. K., Caulfield, M. J., Salsbury, J., Mackenzie, I., Padmanabhan, S., & Brown, M. J. (2015). Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial. The Lancet, 386(10008), 2059-2068. https://doi.org/10.1016/S0140-6736(15)00257-3
  • Williams, B., Mancia, G., Spiering, W., Agabiti Rosei, E., Azizi, M., Burnier, M., Clement, D. L., Coca, A., de Simone, G., Dominiczak, A., Kahan, T., Mahfoud, F., Redon, J., Ruilope, L., Zanchetti, A., Kerins, M., Kjeldsen, S. E., Kreutz, R., Laurent, S., ‚Ķ Brady, A. (2018). 2018 ESC/ESH Guidelines for the man
There is no Supplemental content for this article.

How to Cite This

Sumarlim, Y., Gan, E., Wuryana, D., Pristantiningtyas, M. H., Dharma, H. P., Muchlis, M., … Gondokesumo, M. E. (2023). Therapy of resistant hypertension in patients with chronic kidney disease complications of anemia in hemodialysis: a case report. Jurnal Teknologi Laboratorium, 12(2), 61–65. https://doi.org/10.29238/teknolabjournal.v12i2.444

Article Metrics

Download Statistics

Downloads

Download data is not yet available.

Other Statistics

Verify authenticity via CrossMark

Copyright and Permissions

Creative Commons License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Publishing your paper with Jurnal Teknologi Laboratorium (JTL) means that the author or authors retain the copyright in the paper. JTL granted an exclusive reuse license by the author(s), but the author(s) are able to put the paper onto a website, distribute it to colleagues, give it to students, use it in your thesis etc, even commercially. The author(s) can reuse the figures and tables and other information contained in their paper published by JTL in future papers or work without having to ask anyone for permission, provided that the figures, tables or other information that is included in the new paper or work properly references the published paper as the source of the figures, tables or other information, and the new paper or work is not direct at private monetary gain or commercial advantage.

JTL journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. This journal is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License. This license lets others remix, transform, and build upon the material for any purpose, even commercially.

JTL journal Open Access articles are distributed under this Creative Commons Attribution-ShareAlike 4.0 International License (CC BY-SA). Articles can be read and shared for All purposes under the following conditions:

  • BY: You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • SA:  If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original.

Data Availability

All data generated during this study are included in this published article [and its supplementary information files].